Trade name of the drug: Albendex
Active ingredient (INN): albendazole
Dosage form: tablets
in one tablet contains :
Active ingredient: albendazole – 400.0 mg;
In auxiliary substances: corn starch, gelatin, sodium lauryl sulfate, sodium starch glycolate, crospovidone, microcrystalline cellulose, sodium saccharinate, croscarmellose sodium, magnesium stearate, shell coating “Instacoat Aqua”
Tablet in the form of a capsule, coated from light reddish brown to dark reddish brown biconvex film coat, with a break line on one side and smooth on the other side
Pharmacotherapeutic group: Anthelmintic agent .
ATH code: P02CA03
The drug exhibits anthelmintic activity. Albendazole affects the polymerization of β-tubulin, stops it. As a result, there is a violation of the formation of microtubules in the intestines of helminths, the ability of worms to absorb glucose is suppressed, the normal intracellular migration of organelles, and the synthesis of ATP in their muscle tissue are blocked. The creation of a therapeutic concentration of albendalosis leads to the death of helminths.
The drug is active against adults and larval forms. Albendazole causes the death of nematodes (Necatoramericanus, Strongyloidesstercoralis, Enterobiusvermicularis, Trichuristrichiura, Ascarislumbricoides, Cutaneous Larva Migrans, Ancylostomaduodenale), cestodes (porcine, bovine and dwarf chainworms), trematodes
Indications for use
Albendazole is prescribed for:
– echinococcosis of the peritoneum, liver, lungs;
– contraindications to surgery for cystic echinaccoccosis;
– the need for surgical intervention for cystic echinaccoccosis to reduce the number of cysts;
– arachnoid, intragastric, racemose cysts;
– hookworm disease;
– mixed helminthiasis.
Method of administration and dosage
Albendazole is prescribed orally, after meals. The tablets are washed down with water. The table shows dosages depending on the pathology. Taking laxatives after taking Albendazole is not necessary.
|Pathology||Dosage per day||Number of days|
|Common helminthiases||400 mg (children – 60 mg / 10 kg)||Once|
|Cysticercosis of the brain||800 mg (children – 15 mg / kg)||8-30 days|
|Strongyloidiasis and cestodes||400 mg (200 mg)||3 days with repetition after 3 weeks|
|Ascariasis||400 mg (200 mg)||One-time with repetition through
|Enterobiasis||400 mg (200 mg)||One-time with repetition through
|Hookworm||400 mg (200 mg)||One-time with repetition through
|Giardiasis||400 mg (200 mg)||3 days with repetition after 3 weeks|
Taking Albendazole may be accompanied by undesirable effects:
– an increase in the activity of liver transaminases;
– abdominal pain;
– meningeal symptoms;
– every itch;
– alopecia (reversible);
– impaired renal function.
Albendazole is not prescribed for:
– helminthiasis in children under 2 years of age;
– hypersensitivity to albendazole;
With caution when:
– pathologies of the retina against the background of cysticercosis;
– cirrhosis of the liver;
– oppression of bone marrow hematopoiesis.
Pregnancy: Albendazole is categorically contraindicated in pregnancy, suspected pregnancy.
The plasma concentration of albendazole is increased by praziquantel, dexamethasone, cimetidine.
Excessive doses are characterized by an increase in side symptoms.
Keep out of reach of children and do not use after the expiration date indicated on the package.
1 tablet in a blister strip.
Contoured cell packs of 1 (1 × 1), together with instructions for use, are placed in a cardboard box.
In a dry, dark place, at a temperature not exceeding 25 0 С.
Conditions of dispensing from pharmacies